Sensitive liquid biopsy screening test, designed to effecitively and without intervention analyze blood samples. This test is focused on colorectal, lung tumours together with gastrointestinal tract (GI) or stromal tumours (GISTs). GIST are rare illnesses in which cancers arise in certain cells lining the digestive tract. Recognise GISTs requires a fundamental grasp of the architecture and function of the gastrointestinal tract. Despite the fact that GIST tumours can develop anywhere in the gastrointestinal tract, most instances occur in the stomach and small intestine (60% and 35%, respectively). The rectum, colon, and oesophagus contain the majority of the remaining ones. Only a few develop in the abdomen past the gastrointestinal tract. As a result, screening for CRC in addition to GIST is strongly advised.
The risk of having a GIST is greater in those over 50. Theoretically, these tumours might afflict anybody, although they usually affect individuals over 40.
This screening test is available for purchase only in conjunction with at least one additional liquid biopsy test.
The test can be performed anytime and professional societies have recommendations according to the cancer type. An early detection enables very efficient treatment and recovery. The later the disease is detected, the more complicated is the treatment.
This test can save you time, while each type of cancer may regards different examination(s) like biopsy, x-ray, Computer tomography atd.. Regular screening is important to recognize it in time!
You are 40+
You experienced blood in your stool
You have got CRC in your family history
You loose weight from unknown reasons
You have got inflammatory bowel disease
You have persistent pain or cramps in abdomen
Neurofibromatosis Type 1, Carney-Stratakis Syndrome, Familial GIST Syndrome, Li-Fraumeni Syndrome
After you purchased the test, you get the AveGene ct/cfDNA liquid biopsy somatic & germinal mutations sample collection & transport kit. Arrange the blood draw according to the enclosed instructions.
Send sample to nearest AveGene collection center or to central AveGene laboratory.
GReceive your results in the form of an encrypted PDF report. Request an online consultation if needed.Receive your results in the form of an encrypted PDF report. Request an online consultation if needed.
About GIST cancer
Gastrointestinal stromal tumors (GISTs) are rare tumors that primarily originate in the gastrointestinal tract, most commonly in the stomach and small intestine, accounting for approximately 1-3% of all gastrointestinal tumors, with a higher prevalence in adults. The majority of GISTs contain mutations in the KIT gene, which plays a crucial role in cell growth. Symptoms may include abdominal pain, gastrointestinal bleeding, and a palpable mass, although some patients can be asymptomatic. Diagnosis typically involves imaging studies and biopsy, with immunohistochemical staining for CD117 (KIT protein) being a key diagnostic tool. Treatment often involves surgical removal for localized tumors, while advanced cases may require targeted therapies like imatinib (Gleevec). Prognosis varies based on tumor size, location, and mitotic index, with smaller tumors generally having a better outcome; however, there is a risk of recurrence, necessitating regular follow-up. Ongoing research aims to deepen the understanding of GIST biology and develop more effective treatment options, while various organizations provide resources and support for affected patients and families.
There is no danger to any of your private data on AveGene.
We make sure that even the internal testing is done in secret. In a way, we don't even need to know the patient's name. The molecular state of the blood or plasma sample sent to us is only interpreted with an anonymous sample ID. The person who has the activation card information is the only one who can see the results.
