+ Melanoma

Sensitive liquid biopsy screening test, designed to effecitively and without intervention analyze blood samples. This test is focused on colorectal, lung and Melanoma tumours, which are among the most frequent malignancies globally. A change in an existing mole is generally the first indicator of melanoma. The appearance of a new, darker, or otherwise abnormal-looking growth on the skin. Always see a medical professional if you notice any unusual changes to your skin.

This screening test is available for purchase only in conjunction with at least one additional liquid biopsy test.

Price: €299
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When should i screen?

The melanocytes are the origin of melanoma, a skin cancer. Melanocytes are the skin-coloring pigment-making cells. The name of the pigment is melanin.

Skin that is frequently exposed to sunlight is more likely to develop melanoma. A person's legs, arms, back, and face all fall within this category. Eye melanoma is another possible kind. Inside the body, as in the throat or nose, it might happen very seldom.

It is unclear what causes all melanomas. Sunlight exposure is the leading cause of melanomas. In the sun or in tanning beds and lamps, you can find ultraviolet light, more often known as UV light. Melanoma risk can be reduced by limiting exposure to ultraviolet radiation.

Melanoma seems to be on the rise in women under the age of 40. If you are aware of the signs and symptoms of skin cancer, you may take steps to catch the disease in its early stages and treat it effectively. Early detection is key for effective treatment of melanoma.

You are 40+

You experienced blood in your stool

You have got CRC in your family history

You loose weight from unknown reasons

You have got inflammatory bowel disease

You have persistent pain or cramps in abdomen

Risk Factors
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Sunlight (UV)
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Heavy Metals
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Genetic Predisposition
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Life Style
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Smooking, Alcohol
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Family History
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Obesity
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Possibly associated diseases or conditions

Other Skin Cancers, Familial Atypical Multiple Mole Melanoma (FAMMM) Syndrome, i-Fraumeni Syndrome, Immune System Disorders, Chronic Skin Conditions

How It Works
1.

After you purchased the test, you get the AveGene ct/cfDNA liquid biopsy somatic & germinal mutations sample collection & transport kit. Arrange the blood draw according to the enclosed instructions.

2.

Send sample to nearest AveGene collection center or to central AveGene laboratory.

3.

GReceive your results in the form of an encrypted PDF report. Request an online consultation if needed.

About melanoma

Melanoma is a malignant tumor originating from melanocytes, characterized by atypical, irregularly shaped pigmented cells that invade the dermis and may metastasize. Key genetic alterations include mutations in the BRAF and NRAS genes, which activate the MAPK signaling pathway, as well as changes in tumor suppressor genes like TP53 and CDKN2A. Histologically, melanoma is identified by increased mitotic activity and lymphocytic infiltration. The American Joint Melanoma is a type of skin cancer that originates from melanocytes, the pigment-producing cells responsible for the color of the skin. Committee on Cancer (AJCC) staging system classifies melanoma based on Breslow depth, ulceration status, lymph node involvement, and distant metastasis, with clinical presentations varying from superficial spreading to nodular forms. Prognosis is influenced by factors such as tumor thickness and early detection, with treatment options ranging from surgical excision to immunotherapy and targeted therapies.

REPORTS & HOW TO UNDERSTAND THE TEST RESULTS?
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FAQ

There is no danger to any of your private data on AveGene. 
We make sure that even the internal testing is done in secret. In a way, we don't even need to know the patient's name. The molecular state of the blood or plasma sample sent to us is only interpreted with an anonymous sample ID. The person who has the activation card information is the only one who can see the results. 

Important bodies, resources and partners links
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